Tyro3 carboxyl terminal region confers stability and contains the autophosphorylation sites

Tyro3, a member of TAM receptor tyrosine kinase family has been suggested to be autophosphorylated upon activation. In the current study we mapped the autophosphorylation sites of murine Tyro3 to tyrosine 723 and 756, with K540 being required for its kinase activity. Knockdown of Axl significantly d...

Full description

Bibliographic Details
Main Authors: Shao, Hanshuang (Author), Wells, Alan (Author), Lauffenburger, Douglas A (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: Elsevier, 2018-09-10T18:49:24Z.
Subjects:
Online Access:Get fulltext