Deformability-based cell selection with downstream immunofluorescence analysis

Deformability-based cell selection with downstream immunofluorescence analysis

Mechanical properties of single cells have been shown to relate to cell phenotype and malignancy. However, until recently, it has been difficult to directly correlate each cell's biophysical characteristics to its molecular traits. Here, we present a cell sorting technique for use with a suspen...

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Main Authors: Shaw Bagnall, Josephine (Author), Byun, Sangwon (Author), Miyamoto, David T. (Author), Maheswaran, Shyamala (Author), Stott, Shannon L. (Author), Toner, Mehmet (Author), Kang, Joon Ho (Contributor), Manalis, Scott R (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Physics (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Royal Society of Chemistry (RSC), 2018-09-10T19:39:31Z.
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