Low-volume multiplexed proteolytic activity assay and inhibitor analysis through a pico-injector array

Secreted active proteases, from families of enzymes such as matrix metalloproteinases (MMPs) and ADAMs (a disintegrin and metalloproteinases), participate in diverse pathological processes. To simultaneously measure multiple specific protease activities, a series of parallel enzyme reactions combine...

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Bibliographic Details
Main Authors: Ng, Ee Xien (Author), Jing, Tengyang (Author), Chen, Chia-Hung (Author), Miller, Miles Aaron (Contributor), Lauffenburger, Douglas A (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: Royal Society of Chemistry (RSC), 2018-09-11T14:23:41Z.
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