Quantitative Phosphoproteomics Reveals Wee1 Kinase as a Therapeutic Target in a Model of Proneural Glioblastoma

Quantitative Phosphoproteomics Reveals Wee1 Kinase as a Therapeutic Target in a Model of Proneural Glioblastoma

Glioblastoma (GBM) is the most common malignant primary brain cancer. With a median survival of about a year, new approaches to treating this disease are necessary. To identify signaling molecules regulating GBM progression in a genetically engineered murine model of proneural GBM, we quantified pho...

Full description

Bibliographic Details
Main Authors: Lei, Liang (Author), Bakken, Katrina K. (Author), Sims, Peter A. (Author), Sarkaria, Jann N. (Author), Canoll, Peter (Author), Lescarbeau, Rebecca S. (Contributor), White, Forest M. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), White, Forest M (Contributor)
Format: Article
Language:English
Published: American Association for Cancer Research (AACR), 2018-09-12T17:33:51Z.
Subjects:
Article
Online Access:Get fulltext

Internet

Get fulltext

Similar Items