Network analysis identifies chromosome intermingling regions as regulatory hotspots for transcription

The 3D structure of the genome plays a key role in regulatory control of the cell. Experimental methods such as high-throughput chromosome conformation capture (Hi-C) have been developed to probe the 3D structure of the genome. However, it remains a challenge to deduce from these data chromosome reg...

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Bibliographic Details
Main Authors: Belyaeva, Anastasiya (Contributor), Venkatachalapathy, Saradha (Author), Nagarajan, Mallika (Author), Shivashankar, G. V. (Author), Uhler, Caroline (Contributor)
Other Authors: Massachusetts Institute of Technology. Institute for Data, Systems, and Society (Contributor), Massachusetts Institute of Technology. Laboratory for Information and Decision Systems (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2018-09-12T20:35:31Z.
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