Enhancement of Peptide Vaccine Immunogenicity by Increasing Lymphatic Drainage and Boosting Serum Stability

Enhancement of Peptide Vaccine Immunogenicity by Increasing Lymphatic Drainage and Boosting Serum Stability

Antitumor T-cell responses have the potential to be curative in cancer patients, but the induction of potent T-cell immunity through vaccination remains a largely unmet goal of immunotherapy. We previously reported that the immunogenicity of peptide vaccines could be increased by maximizing delivery...

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Main Authors: Karver, Mark R. (Author), Dinter, Jens (Author), Gall, Sylvie Le (Author), Moynihan, Kelly Dare (Contributor), Holden, Rebecca Lynn (Contributor), Mehta, Naveen (Contributor), Wang, Chensu (Contributor), Liang, Simon (Contributor), Abraham, Wuhbet (Contributor), Melo, Mariane Bandeira (Contributor), Zhang, Angela Q. (Contributor), Li, Na (Contributor), Pentelute, Bradley L. (Contributor), Irvine, Darrell J (Contributor)
Other Authors: Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor), Massachusetts Institute of Technology. Department of Materials Science and Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: American Association for Cancer Research, 2018-09-13T18:20:51Z.
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