The effect of geometric isomerism on the anticancer activity of the monofunctional platinum complex

The effect of geometric isomerism on the anticancer activity of the monofunctional platinum complex

A trans-DDP based monofunctional phenanthridine Pt(ii) complex was synthesized and characterized. Its anticancer activity was studied in vitro on a panel of human cancer cell lines and mouse intestinal cancer organoids. This complex displays significant antitumor properties, with a different spectru...

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Bibliographic Details
Main Authors: Zhou, Wen (Contributor), Almeqdadi, Mohammad (Contributor), Xifaras, Michael (Contributor), Riddell, Imogen Anne (Contributor), Yilmaz, Omer (Contributor), Lippard, Stephen J. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Royal Society of Chemistry (RSC), 2018-09-14T16:19:36Z.
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