Loss of spatial organization and destruction of the pericellular matrix in early osteoarthritis in vivo and in a novel in vitro methodology

Loss of spatial organization and destruction of the pericellular matrix in early osteoarthritis in vivo and in a novel in vitro methodology

Objectives: Current repair procedures for articular cartilage (AC) cannot restore the tissue's original form and function because neither changes in its architectural blueprint throughout life nor the respective biological understanding is fully available. We asked whether two unique elements o...

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Main Authors: Rothdiener, M. (Author), Bast, S. (Author), Uynuk-Ool, T. (Author), Zouhair, S. (Author), Ochs, B.G (Author), De Zwart, P. (Author), Stoeckle, U. (Author), Aicher, W.K (Author), Hart, M.L (Author), Shiozawa, T. (Author), Schenke-Layland, K. (Author), Venkatesan, J.K (Author), Cucchiarini, M. (Author), Madry, H. (Author), Kurz, B. (Author), Felka, Tino (Contributor), Grodzinsky, Alan J (Contributor), Rolauffs, Bernd G (Contributor)
Other Authors: Harvard University- (Contributor), Massachusetts Institute of Technology. Center for Biomedical Engineering (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor)
Format: Article
Language:English
Published: Elsevier BV, 2018-09-17T13:36:44Z.
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