3D microfluidic ex vivo culture of organotypic tumor spheroids to model immune checkpoint blockade

3D microfluidic ex vivo culture of organotypic tumor spheroids to model immune checkpoint blockade

Microfluidic culture has the potential to revolutionize cancer diagnosis and therapy. Indeed, several micro- devices are being developed specifically for clinical use to test novel cancer therapeutics. To be effective, these platforms need to replicate the continuous interactions that exist between...

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Main Authors: Portell, Andrew (Author), Larios, Dalia (Author), Piel, Brandon P. (Author), Mathur, Natasha (Author), Zhou, Chensheng (Author), Coakley, Raven Vlahos (Author), Bartels, Alan (Author), Bowden, Michaela (Author), Herbert, Zach (Author), Gilhooley, Sean (Author), Carter, Jacob (Author), Cañadas, Israel (Author), Thai, Tran C. (Author), Kitajima, Shunsuke (Author), Chiono, Valeria (Author), Paweletz, Cloud P. (Author), Jenkins, Russell W. (Author), Aref, Amir Reza (Contributor), Ivanova, Elena (Contributor), Campisi, Marco (Contributor), Hill, Sarah J (Contributor), Barbie, David (Contributor), Kamm, Roger Dale (Contributor)
Other Authors: Institute for Medical Engineering and Science (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor)
Format: Article
Language:English
Published: Royal Society of Chemistry (RSC), 2018-09-17T18:20:06Z.
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