In vivo detection of drug-induced apoptosis in tumors using Raman spectroscopy

In vivo detection of drug-induced apoptosis in tumors using Raman spectroscopy

We describe a label-free approach based on Raman spectroscopy, to study drug-induced apoptosis in vivo. Spectral-shifts at wavenumbers associated with DNA, proteins, lipids, and collagen have been identified on breast and melanoma tumor tissues. These findings may enable a new analytical method for...

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Bibliographic Details
Main Authors: Jonas, Oliver (Author), Singh, Surya P. (Author), Lammers, Alex (Author), Dasari, Ramachandra R. (Author), So, Peter T. C. (Author), Nguyen, Freddy T. (Contributor), Langer, Robert S (Contributor), Kang, Jeon Woong (Contributor), Cima, Michael J. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Laser Biomedical Research Center (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Cima, Michael J (Contributor)
Format: Article
Language:English
Published: Royal Society of Chemistry, 2018-10-01T13:43:13Z.
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