Virus-driven Inflammation Is Associated With the Development of bNAbs in Spontaneous Controllers of HIV

Virus-driven Inflammation Is Associated With the Development of bNAbs in Spontaneous Controllers of HIV

Background: Understanding the mechanism(s) by which broadly neutralizing antibodies (bNAbs) emerge naturally following infection is crucial for the development of a protective vaccine against human immunodeficiency virus (HIV). Although previous studies have implicated high viremia and associated im...

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Main Authors: Dugast, Anne-Sophie (Author), Lofano, Giuseppe (Author), Moore, Sarah (Author), Hoffner, Michelle (Author), Simek, Melissa (Author), Poignard, Pascal (Author), Seaman, Michael (Author), Suscovich, Todd J. (Author), Pereyra, Florencia (Author), Walker, Bruce D. (Author), Kwon, Douglas S. (Author), Keele, Brandon F. (Author), Alter, Galit (Author), Arnold, Kelly Benedict (Contributor), Lauffenburger, Douglas A (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Lauffenburger (Contributor)
Format: Article
Language:English
Published: Oxford University Press, 2018-10-09T15:14:51Z.
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