Long-term viability and function of transplanted islets macroencapsulated at high density are achieved by enhanced oxygen supply

Transplantation of encapsulated islets can cure diabetes without immunosuppression, but oxygen supply limitations can cause failure. We investigated a retrievable macroencapsulation device wherein islets are encapsulated in a planar alginate slab and supplied with exogenous oxygen from a replenishab...

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Main Authors: Evron, Yoav (Author), Colton, Clark K. (Author), Ludwig, Barbara (Author), Weir, Gordon C. (Author), Zimermann, Baruch (Author), Maimon, Shiri (Author), Neufeld, Tova (Author), Shalev, Nurit (Author), Goldman, Tali (Author), Leon, Assaf (Author), Yavriyants, Karina (Author), Shabtay, Noa (Author), Rozenshtein, Tania (Author), Azarov, Dimitri (Author), DiIenno, Amanda R. (Author), Steffen, Anja (Author), de Vos, Paul (Author), Bornstein, Stefan R. (Author), Barkai, Uriel (Author), Rotem, Avi (Author), Colton, Clark K (Contributor), DiIenno, Amanda Rose (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor)
Format: Article
Language:English
Published: Springer Nature, 2018-10-22T18:49:14Z.
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