Live-cell mapping of organelle-associated RNAs via proximity biotinylation combined with protein-RNA crosslinking

The spatial organization of RNA within cells is a crucial factor influencing a wide range of biological functions throughout all kingdoms of life. However, a general understanding of RNA localization has been hindered by a lack of simple, high-throughput methods for mapping the transcriptomes of sub...

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Bibliographic Details
Main Authors: Kaewsapsak, Pornchai (Contributor), Shechner, David Michael (Author), Mallard, William (Author), Rinn, John L (Author), Ting, Alice Y (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: eLife Sciences Organisation, Ltd., 2018-10-31T18:07:19Z.
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