Blood handling and leukocyte isolation methods impact the global transcriptome of immune cells

Blood handling and leukocyte isolation methods impact the global transcriptome of immune cells

Background Transcriptional profiling with ultra-low input methods can yield valuable insights into disease, particularly when applied to the study of immune cells using RNA-sequencing. The advent of these methods has allowed for their use in profiling cells collected in clinical trials and other stu...

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Main Authors: Goods, Brittany A (Contributor), Vahey, Jacqueline M. (Contributor), Steinschneider, Arthur S (Contributor), Askenase, Michael H (Contributor), Sansing, Lauren (Contributor), Love, Christopher J. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Love, Christopher J (Contributor)
Format: Article
Language:English
Published: BioMed Central, 2018-11-06T17:40:17Z.
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