Mitigation of resource competition in synthetic genetic circuits through feedback regulation

A recurring challenge in the design of genetic circuits is context dependence, the fact that the behavior of a functional module is influenced by the state of the wider cellular milieu with which it interacts. One key player in context dependence is the scarcity of shared cellular resources, especia...

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Bibliographic Details
Main Authors: Hamadeh, Abdullah (Contributor), Del Vecchio, Domitilla (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor)
Format: Article
Language:English
Published: Institute of Electrical and Electronics Engineers (IEEE), 2018-11-16T23:17:23Z.
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