Mitigation of resource competition in synthetic genetic circuits through feedback regulation
A recurring challenge in the design of genetic circuits is context dependence, the fact that the behavior of a functional module is influenced by the state of the wider cellular milieu with which it interacts. One key player in context dependence is the scarcity of shared cellular resources, especia...
Main Authors: | Hamadeh, Abdullah (Contributor), Del Vecchio, Domitilla (Contributor) |
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Other Authors: | Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor) |
Format: | Article |
Language: | English |
Published: |
Institute of Electrical and Electronics Engineers (IEEE),
2018-11-16T23:17:23Z.
|
Subjects: | |
Online Access: | Get fulltext |
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