Linking single-cell measurements of mass, growth rate, and gene expression

Linking single-cell measurements of mass, growth rate, and gene expression

Mass and growth rate are highly integrative measures of cell physiology not discernable via genomic measurements. Here, we introduce a microfluidic platform enabling direct measurement of single-cell mass and growth rate upstream of highly multiplexed single-cell profiling such as single-cell RNA se...

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Bibliographic Details
Main Authors: Pelton, Kristine (Author), De Smet, Frederik (Author), Ligon, Keith L. (Author), Kimmerling, Robert John (Contributor), Prakadan, Sanjay (Contributor), Gupta, Alejandro J. (Contributor), Calistri, Nicholas L (Contributor), Stevens, Mark M. (Contributor), Olcum, Selim A. (Contributor), Cermak, Nathan (Contributor), Drake, Riley (Contributor), Shalek, Alexander K (Contributor), Manalis, Scott R (Contributor)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: BioMed Central, 2018-12-04T15:51:24Z.
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