Structurally modulated codelivery of siRNA and Argonaute 2 for enhanced RNA interference

Structurally modulated codelivery of siRNA and Argonaute 2 for enhanced RNA interference

Small interfering RNA (siRNA) represents a promising class of inhibitors in both fundamental research and the clinic. Numerous delivery vehicles have been developed to facilitate siRNA delivery. Nevertheless, achieving highly potent RNA interference (RNAi) toward clinical translation requires effici...

Full description

Bibliographic Details
Main Authors: Elkayam, Elad (Author), Joshua-Tor, Leemor (Author), Li, Jiahe (Contributor), Wu, Connie (Contributor), Wang, Wade (Contributor), He, Yanpu (Contributor), Hammond, Paula T (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2018-12-07T19:08:59Z.
Subjects:
Article
Online Access:Get fulltext

Internet

Get fulltext

Similar Items