Binding site for coenzyme A revealed in the structure of pyruvate:ferredoxin oxidoreductase from

Pyruvate:ferredoxin oxidoreductase (PFOR) is a microbial enzyme that uses thiamine pyrophosphate (TPP), three [4Fe-4S] clusters, and coenzyme A (CoA) in the reversible oxidation of pyruvate to generate acetyl-CoA and carbon dioxide. The two electrons that are generated as a result of pyruvate decarb...

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Bibliographic Details
Main Authors: Aman, Heather (Author), Can, Mehmet (Author), Ragsdale, Stephen W. (Author), Chen, Yang-Ting (Contributor), Drennan, Catherine L (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2018-12-10T18:42:53Z.
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