Biophysical Constraints Arising from Compositional Context in Synthetic Gene Networks

Biophysical Constraints Arising from Compositional Context in Synthetic Gene Networks

Synthetic gene expression is highly sensitive to intragenic compositional context (promoter structure, spacing regions between promoter and coding sequences, and ribosome binding sites). However, much less is known about the effects of intergenic compositional context (spatial arrangement and orient...

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Bibliographic Details
Main Authors: Yeung, Enoch (Author), Martin, Kyle B. (Author), Ng, Andrew H. (Author), Beck, James L. (Author), Murray, Richard M. (Author), Dy, Aaron James (Contributor), Del Vecchio, Domitilla (Contributor), Collins, James J. (Contributor)
Other Authors: Institute for Medical Engineering and Science (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor), Massachusetts Institute of Technology. Plasma Science and Fusion Center (Contributor)
Format: Article
Language:English
Published: Elsevier BV, 2018-12-17T15:09:39Z.
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