Biophysical Constraints Arising from Compositional Context in Synthetic Gene Networks
Synthetic gene expression is highly sensitive to intragenic compositional context (promoter structure, spacing regions between promoter and coding sequences, and ribosome binding sites). However, much less is known about the effects of intergenic compositional context (spatial arrangement and orient...
Main Authors: | Yeung, Enoch (Author), Martin, Kyle B. (Author), Ng, Andrew H. (Author), Beck, James L. (Author), Murray, Richard M. (Author), Dy, Aaron James (Contributor), Del Vecchio, Domitilla (Contributor), Collins, James J. (Contributor) |
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Other Authors: | Institute for Medical Engineering and Science (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor), Massachusetts Institute of Technology. Plasma Science and Fusion Center (Contributor) |
Format: | Article |
Language: | English |
Published: |
Elsevier BV,
2018-12-17T15:09:39Z.
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Subjects: | |
Online Access: | Get fulltext |
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