Matrilin-1 Is an Inhibitor of Neovascularization

In the course of conducting a series of studies whose goal was to discover novel endogenous angiogenesis inhibitors, we have purified Matrilin-1 (MATN-1) and have demonstrated, for the first time, that it inhibits neovascularization both in vitro and in vivo. Proteins were extracted from cartilage u...

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Bibliographic Details
Main Authors: Foradori, Matthew J. (Author), Harper, Jay (Author), Li, Xin (Author), Tsang, Paul C. W. (Author), Moses, Marsha A. (Author), Chen, Qian (Contributor), Fernandez, Cecilia A (Contributor), Langer, Robert S (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor), McGovern Institute for Brain Research at MIT (Contributor), Sloan School of Management (Contributor), Langer, Robert S. (Contributor)
Format: Article
Language:English
Published: American Society for Biochemistry and Molecular Biology (ASBMB), 2018-12-18T15:13:43Z.
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