Design of Insulin-Loaded Nanoparticles Enabled by Multistep Control of Nanoprecipitation and Zinc Chelation

Design of Insulin-Loaded Nanoparticles Enabled by Multistep Control of Nanoprecipitation and Zinc Chelation

Nanoparticle (NP) carriers provide new opportunities for controlled delivery of drugs, and have potential to address challenges such as effective oral delivery of insulin. However, due to the difficulty of efficiently loading insulin and other proteins inside polymeric NPs, their use has been mostly...

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Bibliographic Details
Main Authors: Chopra, Sunandini (Contributor), Bertrand, Nicolas (Contributor), Lim, Jong-Min (Contributor), Wang, Amy (Contributor), Farokhzad, Omid C (Contributor), Karnik, Rohit (Contributor)
Other Authors: Institute for Medical Engineering and Science (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2018-12-18T19:39:53Z.
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