Lifestyle modifications: coordinating the tRNA epitranscriptome with codon bias to adapt translation during stress responses

Cells adapt to stress by altering gene expression at multiple levels. Here, we propose a new mechanism regulating stress-dependent gene expression at the level of translation, with coordinated interplay between the tRNA epitranscriptome and biased codon usage in families of stress-response genes. In...

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Bibliographic Details
Main Authors: Chan, Cheryl (Author), Begley, Thomas J. (Author), Pham, Phuong M. (Contributor), Dedon, Peter C (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: Biomed Central Ltd, 2019-01-02T20:47:47Z.
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