Microfluidic platform for characterizing TCR-pMHC interactions

Microfluidic platform for characterizing TCR-pMHC interactions

The physical characteristics of the T cell receptor (TCR)-peptide-major histocompatibility complex (pMHC) interaction are known to play a central role in determining T cell function in the initial stages of the adaptive immune response. State-of-the-art assays can probe the kinetics of this interact...

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Main Authors: Stockslager, Max Andrew (Contributor), Hecht, Vivian Chaya (Contributor), Hu, Kevin (Contributor), Aranda-Michel, Edgar C. (Contributor), Kimmerling, Robert John (Contributor), Manalis, Scott R (Contributor), Shaw, Josephine (Author), Payer, Kristofor Robert (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor), Massachusetts Institute of Technology. Microsystems Technology Laboratories (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Bagnall, Josephine W (Contributor), Payer, Kristofor (Contributor)
Format: Article
Language:English
Published: AIP Publishing, 2019-01-04T18:40:52Z.
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