Computational translation of genomic responses from experimental model systems to humans

The high failure rate of therapeutics showing promise in mouse models to translate to patients is a pressing challenge in biomedical science. Though retrospective studies have examined the fidelity of mouse models to their respective human conditions, approaches for prospective translation of insigh...

Full description

Bibliographic Details
Main Authors: Haigis, Kevin M. (Author), Brubaker, Douglas (Contributor), Proctor, Elizabeth A (Contributor), Lauffenburger, Douglas A (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2019-02-21T21:16:34Z.
Subjects:
Online Access:Get fulltext