Inflamed neutrophils sequestered at entrapped tumor cells via chemotactic confinement promote tumor cell extravasation

Inflamed neutrophils sequestered at entrapped tumor cells via chemotactic confinement promote tumor cell extravasation

Systemic inflammation occurring around the course of tumor progression and treatment are often correlated with adverse oncological outcomes. As such, it is suspected that neutrophils, the first line of defense against infection, may play important roles in linking inflammation and metastatic seeding...

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Bibliographic Details
Main Authors: Chen, Michelle B (Contributor), Hajal, Cynthia (Contributor), Benjamin, David Colin (Contributor), Yu, Cathy Y. (Contributor), Azizgolshani, Hesham (Contributor), Hynes, Richard O (Contributor), Kamm, Roger Dale (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Proceedings of the National Academy of Sciences, 2019-02-28T18:56:55Z.
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