Analysis of Single-Cell RNA-Seq Identifies Cell-Cell Communication Associated with Tumor Characteristics

Tumor ecosystems are composed of multiple cell types that communicate by ligand-receptor interactions. Targeting ligand-receptor interactions (for instance, with immune checkpoint inhibitors) can provide significant benefits for patients. However, our knowledge of which interactions occur in a tumor...

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Bibliographic Details
Main Authors: Du, Jinyan (Author), Jiao, Yang (Author), Sawyer, Andrew (Author), Drummond, Daryl C. (Author), Raue, Andreas (Author), Kumar, Manu Prajapati (Contributor), Lagoudas, Georgia K (Contributor), Lauffenburger, Douglas A (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: Elsevier, 2019-03-07T18:56:54Z.
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