Analysis of Single-Cell RNA-Seq Identifies Cell-Cell Communication Associated with Tumor Characteristics
Tumor ecosystems are composed of multiple cell types that communicate by ligand-receptor interactions. Targeting ligand-receptor interactions (for instance, with immune checkpoint inhibitors) can provide significant benefits for patients. However, our knowledge of which interactions occur in a tumor...
Main Authors: | Du, Jinyan (Author), Jiao, Yang (Author), Sawyer, Andrew (Author), Drummond, Daryl C. (Author), Raue, Andreas (Author), Kumar, Manu Prajapati (Contributor), Lagoudas, Georgia K (Contributor), Lauffenburger, Douglas A (Contributor) |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering (Contributor) |
Format: | Article |
Language: | English |
Published: |
Elsevier,
2019-03-07T18:56:54Z.
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Subjects: | |
Online Access: | Get fulltext |
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