Enhancing Humoral Responses Against HIV Envelope Trimers via Nanoparticle Delivery with Stabilized Synthetic Liposomes

Enhancing Humoral Responses Against HIV Envelope Trimers via Nanoparticle Delivery with Stabilized Synthetic Liposomes

An HIV vaccine capable of eliciting durable neutralizing antibody responses continues to be an important unmet need. Multivalent nanoparticles displaying a high density of envelope trimers may be promising immunogen forms to elicit strong and durable humoral responses to HIV, but critical particle d...

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Bibliographic Details
Main Authors: Kulp, Daniel W. (Author), Mutafyan, Andrew A. (Author), Jones, Christopher A. (Author), Menis, Sergey (Author), Georgeson, Erik (Author), Kubitz, Mike (Author), Zhang, Michael H. (Author), Melo, Mariane B. (Author), Silva, Murillo (Author), Yun, Dong Soo (Author), Schief, William R. (Author), Tokatlian, Talar (Contributor), Irvine, Darrell J (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Materials Science and Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2019-03-08T20:58:10Z.
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