Endothelial siRNA delivery in nonhuman primates using ionizable low-molecular weight polymeric nanoparticles
Dysfunctional endothelial cells contribute to the pathophysiology of many diseases, including vascular disease, stroke, hypertension, atherosclerosis, organ failure, diabetes, retinopathy, and cancer. Toward the goal of creating a new RNA-based therapy to correct aberrant endothelial cell gene expre...
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Bibliographic Details
| Main Authors: |
Khan, Omar Fizal
(Author),
Doloff, Joshua C
(Author),
Tsosie, Jonathan
(Author),
Bakthavatchalu, Vasudevan
(Author),
Bodi Winn, Caroline M
(Author),
Haupt, Jennifer
(Author),
Jamiel, Morgan
(Author),
Langer, Robert S
(Author),
Anderson, Daniel Griffith
(Author),
Kowalski, Piotr S
(Author) |
|---|
| Other Authors: |
Massachusetts Institute of Technology. Department of Chemical Engineering
(Contributor),
Massachusetts Institute of Technology. Division of Comparative Medicine
(Contributor),
Harvard University-
(Contributor),
Massachusetts Institute of Technology. Institute for Medical Engineering & Science
(Contributor),
Massachusetts Institute of Technology. Department of Biological Engineering
(Contributor),
Koch Institute for Integrative Cancer Research at MIT
(Contributor) |
|---|
| Format: | Article
|
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| Language: | English |
|---|
| Published: |
American Association for the Advancement of Science (AAAS),
2019-08-09T16:26:39Z.
|
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| Subjects: | |
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| Online Access: | Get fulltext
|
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