Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis

Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis

Blood cell formation is classically thought to occur through a hierarchical differentiation process, although recent studies have shown that lineage commitment may occur earlier in hematopoietic stem and progenitor cells (HSPCs). The relevance to human blood diseases and the underlying regulation of...

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Main Authors: Khajuria, Rajiv K. (Author), Munschauer, Mathias (Author), Ulirsch, Jacob C. (Author), Fiorini, Claudia (Author), Ludwig, Leif S. (Author), McFarland, Sean K. (Author), Abdulhay, Nour J. (Author), Specht, Harrison (Author), Keshishian, Hasmik (Author), Mani, Denkanikota R (Author), Jovanovic, Marko (Author), Ellis, Steven R. (Author), Fulco, Charles P. (Author), Engreitz, Jesse Michael (Author), Schutz, Sabina (Author), Lian, John (Author), Gripp, Karen W. (Author), Weinberg, Olga K. (Author), Pinkus, Geraldine S. (Author), Gehrke, Lee (Author), Regev, Aviv (Author), Lander, Eric Steven (Author), Gazda, Hanna T. (Author), Lee, Winston Y. (Author), Panse, Vikram G. (Author), Sankaran, Vijay G. (Author), Carr, Steven A (Author)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Harvard University- (Contributor)
Format: Article
Language:English
Published: Elsevier BV, 2019-11-08T21:17:51Z.
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