Rationally Designed Polycationic Carriers for Potent Polymeric siRNA-Mediated Gene Silencing
The delivery of small interfering RNA (siRNA) remains a major hurdle for the clinical translation of RNA interference (RNAi) therapeutics. Because of its low valency and rigid nature, siRNA typically requires high excesses of cationic delivery materials to package it stably and deliver it to the cyt...
| Main Authors: | , , , |
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| Other Authors: | , , |
| Format: | Article |
| Language: | English |
| Published: |
American Chemical Society,
2019-11-12T18:00:05Z.
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| Subjects: | |
| Online Access: | Get fulltext |