Non-viral delivery of CRISPR/Cas9 complex using CRISPR-GPS nanocomplexes

Non-viral delivery of CRISPR/Cas9 complex using CRISPR-GPS nanocomplexes

There is a critical need for the development of safe and efficient delivery technologies for CRISPR/Cas9 to advance translation of genome editing to the clinic. Non-viral methods that are simple, efficient, and completely based on biologically-derived materials could offer such potential. Here we re...

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Bibliographic Details
Main Authors: Jain, Piyush Kumar (Author), Lo, Justin H. (Author), Rananaware, Santosh (Author), Downing, Marco (Author), Panda, Apekshya (Author), Tai, Michelle (Author), Raghavan, Srivatsan (Author), Fleming, Heather (Author), Bhatia, Sangeeta N (Author)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Broad Institute of MIT and Harvard (Contributor)
Format: Article
Language:English
Published: Royal Society of Chemistry (RSC), 2020-01-21T20:28:58Z.
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