Site-Selective Cysteine-Cyclooctyne Conjugation
We report a site-selective cysteine-cyclooctyne conjugation reaction between a seven-residue peptide tag (DBCO-tag, Leu-Cys-Tyr-Pro-Trp-Val-Tyr) at the N or C terminus of a peptide or protein and various aza-dibenzocyclooctyne (DBCO) reagents. Compared to a cysteine peptide control, the DBCO-tag inc...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley,
2020-01-21T22:20:04Z.
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Subjects: | |
Online Access: | Get fulltext |