Mediator and RNA polymerase II clusters associate in transcription-dependent condensates

Mediator and RNA polymerase II clusters associate in transcription-dependent condensates

Models of gene control have emerged from genetic and biochemical studies, with limited consideration of the spatial organization and dynamics of key components in living cells. We used live-cell superresolution and light-sheet imaging to study the organization and dynamics of the Mediator coactivato...

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Bibliographic Details
Main Authors: Cho, Won-ki (Author), Spille, Jan Hendrik (Author), Hecht, Micca (Author), Lee, Choongman (Author), Li, Charles Han (Author), Grube, Valentin (Author), Cisse, Ibrahim I (Author)
Other Authors: Massachusetts Institute of Technology. Department of Physics (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), MIT Materials Research Laboratory (Contributor)
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS), 2020-02-05T20:50:27Z.
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