Discovery of novel bacterial queuine salvage enzymes and pathways in human pathogens

Queuosine (Q) is a complex tRNA modification widespread in eukaryotes and bacteria that contributes to the efficiency and accuracy of protein synthesis. Eukaryotes are not capable of Q synthesis and rely on salvage of the queuine base (q) as a Q precursor. While many bacteria are capable of Q de nov...

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Bibliographic Details
Main Author: Dedon, Peter C. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Center for Environmental Health Sciences (Contributor)
Format: Article
Language:English
Published: Proceedings of the National Academy of Sciences, 2020-03-31T18:57:30Z.
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