Sequestration of microRNA-mediated target repression by the Ago2-associated RNA-binding protein FAM120A

Sequestration of microRNA-mediated target repression by the Ago2-associated RNA-binding protein FAM120A

Argonaute (Ago) proteins interact with various binding partners and play a pivotal role in microRNA (miRNA)-mediated silencing pathways. By utilizing immunoprecipitation followed by mass spectrometry to determine cytoplasmic Ago2 protein complexes in mouse embryonic stem cells (mESCs), we identified...

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Bibliographic Details
Main Authors: Kelly, Timothy J. (Author), Suzuki, Hiroshi I. (Author), Zamudio, Jesse R. (Author), Suzuki, Megumu (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Cold Spring Harbor Laboratory Press, 2020-04-07T16:39:46Z.
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