Reactive metabolite production is a targetable liability of glycolytic metabolism in lung cancer
Increased glucose uptake and metabolism is a prominent phenotype of most cancers, but efforts to clinically target this metabolic alteration have been challenging. Here, we present evidence that lactoylglutathione (LGSH), a byproduct of methylglyoxal detoxification, is elevated in both human and mur...
| Main Authors: | , , , , , , , |
|---|---|
| Other Authors: | , , |
| Format: | Article |
| Language: | English |
| Published: |
Springer Science and Business Media LLC,
2020-04-08T13:24:46Z.
|
| Subjects: | |
| Online Access: | Get fulltext |