Activation of PASK by mTORC1 is required for the onset of the terminal differentiation program

Activation of PASK by mTORC1 is required for the onset of the terminal differentiation program

During skeletal muscle regeneration, muscle stem cells (MuSCs) respond to multiple signaling inputs that converge onto mammalian target of rapamycin complex 1 (mTORC1) signaling pathways. mTOR function is essential for establishment of the differentiationcommitted progenitors (early stage of differe...

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Main Authors: Kang, Seong Anthony Woo (Author), Sabatini, David M. (Author)
Other Authors: Whitehead Institute for Biomedical Research (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Proceedings of the National Academy of Sciences, 2020-04-16T14:50:57Z.
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