DEPTOR modulates activation responses in CD4+ T cells and enhances immunoregulation following transplantation
DEPTOR is an evolutionarily conserved cell-intrinsic binding partner of mTOR that functions as a negative regulator of signaling responses. In this study, we show that DEPTOR is expressed within CD4 + T cells, and we observed that its relative level of expression modulates differentiation as well as...
Main Author: | Sabatini, David M. (Author) |
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Other Authors: | Whitehead Institute for Biomedical Research (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor) |
Format: | Article |
Language: | English |
Published: |
Wiley,
2020-04-16T14:56:39Z.
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Subjects: | |
Online Access: | Get fulltext |
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