NUFIP1 is a ribosome receptor for starvation-induced ribophagy

NUFIP1 is a ribosome receptor for starvation-induced ribophagy

The lysosome degrades and recycles macromolecules, signals to the master growth regulator mTORC1 [mechanistic target of rapamycin (mTOR) complex 1], and is associated with human disease.We performed quantitative proteomic analyses of rapidly isolated lysosomes and found that nutrient levels and mTOR...

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Main Authors: Wyant, Gregory A. (Author), Abu-Remaileh, Monther (Author), Frenkel, Evgeni M. (Author), Laqtom, Nouf N. (Author), Dharamdasani, Vimisha (Author), Lewis, Caroline A. (Author), Chan, Sze Ham (Author), Sabatini, David M. (Author)
Other Authors: Whitehead Institute for Biomedical Research (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS), 2020-04-17T13:25:35Z.
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