Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing bisphosphonates
Nitrogen-containing-bisphosphonates (N-BPs) are a class of drugs widely prescribed to treat osteoporosis and other bone-related diseases. Although previous studies have established that N-BPs function by inhibiting the mevalonate pathway in osteoclasts, the mechanism by which N-BPs enter the cytosol...
Main Authors: | , , |
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Other Authors: | , , |
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications, Ltd,
2020-04-21T12:15:25Z.
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Subjects: | |
Online Access: | Get fulltext |