Clostridioides difficile-Associated Antibiotics Alter Human Mucosal Barrier Functions by Microbiome-Independent Mechanisms

A clinically relevant risk factor forClostridioides difficile-associated dis-ease (CDAD) is recent antibiotic treatment. Although broad-spectrum antibioticshave been shown to disrupt the structure of the gut microbiota, some antibioticsappear to increase CDAD risk without being highly active against...

Full description

Bibliographic Details
Main Authors: Kester, Jemila C. (Author), Brubaker, Douglas K. (Author), Velazquez, Jason (Author), Wright, Charles (Author), Lauffenburger, Douglas A. (Author), Griffith, Linda G. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: American Society for Microbiology, 2020-04-21T17:37:04Z.
Subjects:
Online Access:Get fulltext