Small and Large Ribosomal Subunit Deficiencies Lead to Distinct Gene Expression Signatures that Reflect Cellular Growth Rate

In this issue of Molecular Cell, Cheng et al. report specific and dose-dependent gene expression changes resulting from decreased ribosome levels, including distinct gene expression signatures resulting from loss of genes encoding members of either the large or small ribosomal subunit.

Bibliographic Details
Main Authors: Mertins, Philipp (Author), Regev, Aviv (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Elsevier BV, 2020-05-05T16:57:59Z.
Subjects:
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