Emerging Evidence of Chromosome Folding by Loop Extrusion

Emerging Evidence of Chromosome Folding by Loop Extrusion

Chromosome organization poses a remarkable physical problem with many biological consequences: How can molecular interactions between proteins at the nanometer scale organize micron-long chromatinized DNA molecules, insulating or facilitating interactions between specific genomic elements? The mecha...

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Bibliographic Details
Main Authors: Fudenberg, Geoffrey (Author), Abdennur, Nezar Alexander (Author), Imakaev, Maxim (Author), Goloborodko, Anton (Author), Mirny, Leonid A. (Author)
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program (Contributor), Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Massachusetts Institute of Technology. Department of Physics (Contributor)
Format: Article
Language:English
Published: Cold Spring Harbor Laboratory, 2020-05-06T14:42:49Z.
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