Emerging Evidence of Chromosome Folding by Loop Extrusion
Chromosome organization poses a remarkable physical problem with many biological consequences: How can molecular interactions between proteins at the nanometer scale organize micron-long chromatinized DNA molecules, insulating or facilitating interactions between specific genomic elements? The mecha...
Main Authors: | Fudenberg, Geoffrey (Author), Abdennur, Nezar Alexander (Author), Imakaev, Maxim (Author), Goloborodko, Anton (Author), Mirny, Leonid A. (Author) |
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Other Authors: | Massachusetts Institute of Technology. Computational and Systems Biology Program (Contributor), Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Massachusetts Institute of Technology. Department of Physics (Contributor) |
Format: | Article |
Language: | English |
Published: |
Cold Spring Harbor Laboratory,
2020-05-06T14:42:49Z.
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Subjects: | |
Online Access: | Get fulltext |
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