Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq
Gliomas with histone H3 lysine27-to-methionine mutations (H3K27M-glioma) arise primarily in the midline of the central nervous system of young children, suggesting a cooperation between genetics and cellular context in tumorigenesis. Although the genetics of H3K27M-glioma are well characterized, the...
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Other Authors: | , |
Format: | Article |
Language: | English |
Published: |
American Association for the Advancement of Science (AAAS),
2020-05-06T15:28:49Z.
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Online Access: | Get fulltext |