Implications of human genetic variation in CRISPR-based therapeutic genome editing

Implications of human genetic variation in CRISPR-based therapeutic genome editing

CRISPR-Cas genome-editing methods hold immense potential as therapeutic tools to fix disease-causing mutations at the level of DNA. In contrast to typical drug development strategies aimed at targets that are highly conserved among individual patients, treatment at the genomic level must contend wit...

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Main Authors: Scott, David A (Author), Zhang, Feng (Author)
Other Authors: Broad Institute of MIT and Harvard (Contributor), McGovern Institute for Brain Research at MIT (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: Springer Nature, 2020-05-11T18:38:40Z.
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