Enhanced phosphocholine metabolism is essential for terminal erythropoiesis

Red cells contain a unique constellation of membrane lipids. Although much is known about regulated protein expression, the regulation of lipid metabolism during erythropoiesis is poorly studied. Here, we show that transcription of PHOSPHO1, a phosphoethanolamine and phosphocholine phosphatase that...

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Bibliographic Details
Main Authors: Huang, Nai-Jia (Author), Lin, Chung-Yueh (Author), Pishesha, Novalia (Author), Lewis, Caroline A. (Author), Freinkman, Elizaveta (Author), Lodish, Harvey (Author)
Other Authors: Whitehead Institute for Biomedical Research (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: American Society of Hematology, 2020-05-13T14:10:46Z.
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